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Friday, June 29, 2012

Weight loss medicine

Sibutramine
Indication:
    Management of obesity for weight loss.It should be use in conjunction with a reduced calorie diet.

Mechanism of action:
     It is a nor-epinephrine, serotonin and dopamine re-uptake inhibitor.

Dosage:
     Adults:The recommended starting dose is 10mg once daily with or  without food.If there is inadequate weight loss, the dose may be titrated  after four weeks to a total of 15mg daily.Doses above 15mg daily  are not recommended.The 5mg dose should be reserved for patients who do not tolerate the 10mg dose.

Contraindications:
      Hypersensitivity,patients receiving MAO inhibitors,patients are taking other drug, anorexia  
     
Drug Interactions:
      Dangerous interaction can occur with monoamine oxidase inhibitors(MAOs) such as selective serotonin reuptake inhibitor and Antidepressants such as fluoxetine.Caution should be excised when sibutramine administration with other drugs that inhibits cytochrorme P450-3A4 antibiotics ketoconazole & erthromycin, cimetidine, alcohol, warfarin, phenytoin, lithium, sumatriptan or tryptophan.




weight loss medicine
 Adverse Effects: 
      Dry mouth, anorexia, insomnia, constipation, diarrhea, flatulence, gastroenteritis, peripheral o edema, arthritis, agitation, hypertonia,  bronchits, pruritis, & menstrual disorders.


Special Precautions:
       History of coronary artery disease, congestive heart failure, arrhythmia or stroke, narrow angle glaucoma.

Saturday, June 23, 2012

Medicine to loss weight

Amylofix 
Introduction:
     In today world weight management has become more of a health-related issue then cosmetic issue.Obesity,it is often not a stand-alone problem but associated with complication like heart disease,diabetes,arthritis,breathing problem etc.As the number of clinic increases the rate of the people also increases at alarming rate both in developed and developing countries,to control the excess calorie management it should be given more importance and necessary measures.
      according to the average Indian diet restrictions may not be suitable.The Traditional Indian cuisines are heavily love the complex carbohydrates,which are the factors increasing the body weight of the every individual.And this kind of lifestyle of today encourages a inactive lifestyle,leaving little room for exercise.To reduce the weight the medications claim for debatable.The answer to all this situation would be drug that would effectively help to control the calorie of the body.Without necessitating wide changes in ones food and lifestyle habits and yet its safe and efficacious.


Product Description:
     Amylofix contains bio-active extract from Phaseolus Valgaris its commonly known as white kidney bean and acts by medically proven strategy to block extra calorie produce in the body. 



Medical Rationale:
      The role of amylase in the metabolism of carbohydrates is well accepts.The excess carbohydrates in the diet is ultimately changed into fats and stored in the body.The enzymes that catalyze the conversion of starch(a polysaccharide) into sugar molecules(monosaccharide) are called amylases.
       The name Amylofix suggests,as an amylase inhibitor that inhibits the digestion of starch and hence the absorption of glucose.The seeds of Phaseolus Vulgaris contain an inhibitor of alpha-amylase.This alpha amylase inhibitor is identified in the protein fraction of the bean.This protein binds with the active sites of alpha amylase an prevents the starch metabolizing activity;hence it is also called as the ''Starch Blocker''.


    Efficacy And Safety data:
          A student to assess the effectiveness of the bio-active extract from Phaseolus  Valgaris  in weight  control,in 60 overweight (5-15kg) healthy human volunteers (males and females;aged 20-45 yrs) concluded that the extract has a demonstrable capability to reduce weight through fat-body mass reduction via reduced absorption of complex carbohydrates.Volunteers were asked to take it before meals rich in complex carbohydrates and their weights were registered on day 10,20 and 30.At the end of this study,results brought out that the product was associated with a 3.5kg reduction in body weight,along with a10.45% reduction in fat body mass without significant modifications of lean body mass.Results also highlighted a 11.63% reduction of adipose membrane,a 3.44% reduction of waist line,a 1.39% reduction of hip circumference and a 1.44%reduction of thigh circumference.The product also had good tolerability along with proven efficacy. 
    Indication:
       Amylofix can be effectively used in all obese patients to reduce and control excess fat and thus lowering the risk of heart,liver,gall bladder diseases,diabetes,arthritis,breathing disorders,problem with conception etc.and other problems associated with obesity.It can be used to achieve the desired waist circumference,waist to hip ratio and body mass index proportionate to their height and age without starving and strenuous exercise.However,moderate exercise and diet control will have synergistic action with Amylofix for better control and long lasting effects.Its blocks 65-75% calories from starch.
       Amylofix  is not an appetite suppressant or carbohydrate tolerance and reduces postprandial glucose levels,so significantly reduces the level of triglycerides.


   Dosage:
         Two tablets twice or thrice a day (or with every major meal) for 2-3 months for best result half an hrs before a meal.Don't take beyond 6 tablets a day.


   Adverse Effects:
          Serious  side effects are not reported in therapeutic dosages.


   Pregnancy And Lactation:
           Expectant and nursing mothers should consult a physician before using the product.


    Brand:
           Amylofix
    Presentation:
            Bottle pack of 84 tabelts.

Thursday, June 21, 2012

How weight is develope in our body

 weight is one type of disease which grow suddenly or it may grow step by step.weight is measure in calories.And its develop in the body by the growth of inner muscles.Mostly weight is gained by eating the food which have lots of calories and fat eg.lots of   oil having food and chocolate and sweet which contain high amount of calories.
Weight is also gained by leaving the body free and being lazy and having no body exercise.A most interesting thing "once the t.v reporter asked a lady about her weight and the women replay that,she use to do work and also she used to have diet food but then to her weight increases the reason was that weight can be increase suddenly too.weigh is a latency period.Being fat is a common condition,especially  when food supply is plenty but the lifestyle is sedentary.People having more weight causes the following effects,



  • Th fat present in the body increases
  • Muscles mass of body increases
  • The body hydration level increases
  • Increases in breast
All the above effects occur  when weight is increase in our body.


Causes:
Weight gained in the body causes many problem related to sink,heart,liver,brain,stomach etc all this important organs of body caused by over weigh.
We seem that our parents use to say that chew the food properly.scientist prove that chewing food properly have no digestion problem.It can control the diabetes. Diabetes is one of the diseases which attacts the people of develop country because in that country the life style of the people is very smooth,they give stress to their mind but their body is in relax form.so this result in weight gained and cause .diabetes.As diabetes is formed by increase in insulin in the body but  diabetes loss the wight of the people.It make the body thin and decrease the fat.The most causing thing is the skin problem due to the high amount of  fat and calories present in the body  the skin faces many problems like pimples,spots,oily face and cancer too.


Effects:
Weight gained effects lifestyle of human being.Since the person having fat body mostly his/her community  response the negative behavior to him/her  and the reason the person who have a huge body feel uncomfortable and unhappy.The research has been found that  weight increases to  the result ''overweight'' and ''obesity'' all this risks to increase the following conditions:
  • Coronary heat disease 
  • 2 types of diabetes
  • Cancers (endometrial,breast,colon)
  • Hypertension (high blood pressure)
  • Dyslipidemai (high cholesterol or high level of triglycerides)
  • stroke
  • Desease of liver and gallbladder
  • Sleep apnea and respiratory problem
  • Osteoarthritis (a degeneration of cartilage and its underlying bone within a joint)
  • Gynecological problems (abnormal menses,infertility)

*Over weight is defined as a body mass index (BMI) of 25 or higher;obesity is defined as a BMI of 30 or higher.